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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HELQ
All Species:
5.76
Human Site:
S602
Identified Species:
12.67
UniProt:
Q8TDG4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDG4
NP_598375.2
1101
124175
S602
E
M
I
C
K
F
L
S
K
E
Y
L
K
H
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104832
1101
124326
S602
E
M
I
C
K
F
L
S
K
E
Y
L
K
H
K
Dog
Lupus familis
XP_544959
1072
121306
K585
L
K
H
R
E
K
E
K
H
E
V
I
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPA6
1069
119080
L579
K
C
E
V
I
K
S
L
R
N
I
G
N
G
K
Rat
Rattus norvegicus
NP_001014156
1065
118695
N577
E
L
I
K
S
L
R
N
V
G
H
G
K
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517710
972
107104
L505
D
G
S
F
C
P
I
L
K
H
T
V
P
F
G
Chicken
Gallus gallus
XP_420565
1048
116823
I577
E
K
E
K
Q
D
L
I
K
N
L
K
D
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691411
1010
112859
S543
I
L
L
G
E
L
K
S
S
G
N
G
S
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648178
1051
117314
E582
H
S
G
L
T
T
D
E
R
K
Y
I
E
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022911
923
102951
D456
D
N
D
D
E
R
M
D
A
V
L
K
Q
C
I
Sea Urchin
Strong. purpuratus
XP_796097
1147
129034
C668
Q
N
V
A
E
N
I
C
R
Y
I
P
R
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.9
83.1
N.A.
75.1
75.3
N.A.
56.6
61.5
N.A.
54.7
N.A.
36.9
N.A.
32.7
40.7
Protein Similarity:
100
N.A.
98.7
90.2
N.A.
84.4
84.9
N.A.
68
74.3
N.A.
71.1
N.A.
56.9
N.A.
51.4
59.7
P-Site Identity:
100
N.A.
100
13.3
N.A.
6.6
20
N.A.
6.6
20
N.A.
6.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
N.A.
100
33.3
N.A.
20
40
N.A.
26.6
26.6
N.A.
26.6
N.A.
33.3
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
10
0
19
10
0
0
10
0
0
0
0
0
10
19
% C
% Asp:
19
0
10
10
0
10
10
10
0
0
0
0
10
0
0
% D
% Glu:
37
0
19
0
37
0
10
10
0
28
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
19
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
10
10
0
0
0
0
0
19
0
28
0
10
19
% G
% His:
10
0
10
0
0
0
0
0
10
10
10
0
0
19
0
% H
% Ile:
10
0
28
0
10
0
19
10
0
0
19
19
0
10
10
% I
% Lys:
10
19
0
19
19
19
10
10
37
10
0
19
37
0
37
% K
% Leu:
10
19
10
10
0
19
28
19
0
0
19
19
0
10
10
% L
% Met:
0
19
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
10
0
10
0
19
10
0
10
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
10
0
10
10
0
28
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
10
0
10
28
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
10
0
0
19
0
% T
% Val:
0
0
10
10
0
0
0
0
10
10
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
28
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _